Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug–Drug–Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole

Summary

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Authors: Denise Türk, Nina Hanke, Sarah Wolf, Sebastian Frechen, Thomas Eissing, Thomas Wendl, Matthias Schwab, Thorsten Lehr

Journal title: Clinical Pharmacokinetics

Journal number: 58/12

Journal publisher: Adis International Ltd.

Published year: 2019

Published pages: 1595-1607

DOI identifier: 10.1007/s40262-019-00777-x

ISSN: 0312-5963