Ethical approval from overseeing Ethical Committees and Review Boards

The protocol will be submitted for ethical approval in the country of the sponsor (Belgium), at the Institutional Review Boards/Ethics Committee of other research partners where applicable, to other research partners (not in consortium but instrumental for the implementatio of the action) and to national ethics committees with identified or potential study sites (Guinea foreseen at the time of writing this Grant Agreement). The provisional list of concerned bodies is as follows: • WHO Ethical Research Committee (ERC) ; • Institutional Review Board (IRB) of the ITM, Antwerp, Belgium; • Ethics Committee of Antwerp University Hospital, Belgium (accredited by Belgian authorities); • Ethical Review Board of MSF; • Interventions Research Ethics Committee of LSHTM;In Guinea, a special research ethics committee dedicated to Ebola has been organized recently at national level; the WHO participates and is playing an active role. • Sierra Leone is a member country of AVAREF, a WHO/AFRO-led collaboration of National Ethics Committees and National Regulatory Authorities , started for of vaccines’ development /. This is not a joint decision making body, but it brings the relevant experts from the 23 countries together, plus external expert facilitators if needed, to discuss the applications in a peer group. Through AVAREF, WHO plans to support all the EDV-affected countries by convening joint reviews of applications. all the ethical approvals will be provided to the Commission as soon as they are obtained.