A high-throughput functional analysis system (RIgORouS)

A high-throughput functional analysis system (RIgORouS) for 11 BC-HR genes. The final analysis pipeline (RIgORouS) exploits three read-out systems (Figure 3.1d): 1. RAD51 foci analysis 2. Analysis of homologous recombination 3. Analysis of sensitivity to PARPi