Spaciant-based solvent dispersion and unification for cascade 4

Smart solvents, such as supercritical CO2, ionic liquids and fluorous solvents (where needed thermomorphic solvents), will be used to allow the operation of two orthogonal catalysts in close proximity (i.e., in one reactor), which however cannot be dissolved in the same solvent. After reaction, by external stimulus such as cooling down or releasing CO2 gas, the catalysts and their respective solvents will be separated. For Cascade 4, a chemo and biocatalyst will be treated this way. The solvents need to be selected in such way, that reactants and products also will remain in different phases. Then, there is no need for product and catalyst separation, but is rather “automatically” achieved. The investigations follow a generic aim beyond the catalysts and reactants of Cascade 4.There is a multitude of spaciants combination possible for a multitude of processing and purification tasks; some of these will be tested. TUE has complete overview over all relevant literature and made two reviews about, see the following non-published table (shown first time here).