. Sustainability assessment

Life-cycle assessment First, green chemistry indices established in pharmaceutical industry will be applied. The process mass index, e.g., is suited for focused judgement, e.g. on the efficiency in minimizing solvents. For deeper, holistic analysis in a cradle-to-process gate manner and beyond (cradle-to-cradle), life-cycle assessment will be exerted using Umberto and Gabi softwares. Key is here to have robust data sets implemented in the life-cycle inventory. Cost modelling Operational as well as well as capital costs are determined. This allows to calculate life-cycle costs and to plot this versus the life-cycle impact following BASF eco-efficiency approach [Uhlman, Saling, CEP, 2010] Cash-flow analysis will, in addition, reveal the net-present value and let deduce the time need for depreciation of the capital costs.