Hit-optimization using target-directed dynamic combinatorial chemistry: development of inhibitors of the anti-infective target 1-deoxy-d-xylulose-5-phosphate synthase

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Authors: Ravindra P. Jumde, Melissa Guardigni, Robin M. Gierse, Alaa Alhayek, Di Zhu, Zhoor Hamid, Sandra Johannsen, Walid A. M. Elgaher, Philipp J. Neusens, Christian Nehls, Jörg Haupenthal, Norbert Reiling Anna K. H. Hirsch

Journal title: Chemical Science

Journal number: 20416520

Journal publisher: Royal Society of Chemistry

Published year: 2021

DOI identifier: 10.1039/d1sc00330e

ISSN: 2041-6520