A first-in-class Polymerase Theta Inhibitor selectively targets Homologous-Recombination-Deficient Tumors

Summary

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Authors: Jia Zhou, Camille Gelot , Constantia Pantelidou, Adam Li, Hatice Yücel, Rachel E Davis, Anniina Farkkila, Bose Kochupurakkal, Aleem Syed, Geoffrey I Shapiro, John A Tainer, Brian S J Blagg, Raphael Ceccaldi, Alan D D'Andrea

Journal title: Nature Cancer

Journal publisher: Springer Nature

Published year: 2021

Published pages: 598–610.

DOI identifier: 10.1038/s43018-021-00203-x

ISSN: 2662-1347