Periodic Reporting for period 3 - EpigeneticScars (Understanding DSB repair from pathway choice to long term effects and their consequences.)

DNA double-strand breaks (DSB) are critical genomic lesions, and reduced DSB repair efficiency is associated with age-related disease development, like cancer, immunodeficiencies Alzheimer’s and Parkinson´s. Once DSB occurs, the DNA Damage Response (DDR) is initiated by...