Periodic Reporting for period 2 - MORE2ADA2 (Multi-omics research applied to Human ADA2 deficiency and beyond)

Human adenosine deaminase type 2 (ADA2) deficiency (DADA2) is a rare inborn error of immunity, caused by genetic pathogenic variants in the ADA2 gene. DADA2 patients suffer from vasculitis with diverse manifestations ranging from stroke (due too ischemia or bleeding) to severe...