Periodic Reporting for period 1 - CURIE (C53 and Ufmylation Regulation In Endoplasmic Reticulum-Autophagy (ER-phagy))

Persistent cellular stress impairs cell fitness and lifespan. When stress happens, protein aggregates will be formed, these could be cleared by the essential and fundamental cellular protein quality control pathway called autophagy. Defects in autophagy are linked to diverse...