Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice

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Authors: ANDREW C. HUNT, JAMES BRETT CASE, YOUNG-JUN PARK, LONGXING CAO, KEJIA WU, ALEXANDRA C. WALLS, ZHUOMING LIU, JOHN E. BOWEN, HSIEN-WEI YEH, SHALLY SAINI, LOUISA HELMS, YAN TING ZHAO, TIEN-YING HSIANG, TYLER N. STARR, INNA GORESHNIK, LISA KOZODOYLAUREN CARTER, RASHMI RAVICHANDRAN, LYDIA B. GREENWADIM L. MATOCHKO, CHRISTY A. THOMSONBASTIAN VÖGELI, ANTJE KRÜGER, LAURA A. VANBLARGAN, RITA E. CHEN, BAO

Journal title: SCIENCE TRANSLATIONAL MEDICINE

Journal number: 19466234

Journal publisher: American Association for the Advancement of Science

Published year: 2022

DOI identifier: 10.1126/scitranslmed.abn1252

ISSN: 1946-6234