Periodic Reporting for period 1 - nAChR PAM-to-gate (Gating mechanism and pharmacological modulation of nicotinic acetylcholine receptors)

Neurotransmitter-gated ion channels are responsible for fast chemical neurotransmission at synapses, i.e. the specialized chemical junction enabling the communication between excitable cells like neurons. Amongst these ion channels, the superfamily of pentameric ligand-gated...