Periodic Reporting for period 1 - Za-AV (Determination of physiologically relevant RNA substrate(s) and design of small-molecule inhibitors for Zα domains as potential intervention strategies for viral infections and autoimmunity)

The problems being addressed by the actions pertained to finding out the substrate specificity of Z-alpha domains using RNA-seq analysis and the subsequent biophysical characterisation of the protein and its cognate substrate/s.This issue is important to society because viral...