Periodic Reporting for period 1 - DUX4 (Function of DUX4 in skeletal muscle and non-muscle tissues)

DUX4 expression in skeletal muscle is associated with the development of facioscapulohumeral muscular dystrophy (FSHD). DUX4 encodes a transcription factor that plays an important role in the initiation of gene expression after fertilization in mammals. As FSHD patients mainly...