Protein conformational flexibility modulates kinetics and thermodynamics of drug binding

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Authors: M. Amaral, D. B. Kokh, J. Bomke, A. Wegener, H. P. Buchstaller, H. M. Eggenweiler, P. Matias, C. Sirrenberg, R. C. Wade, M. Frech

Journal title: Nature Communications

Journal number: 8/1

Journal publisher: Nature Publishing Group

Published year: 2017

DOI identifier: 10.1038/s41467-017-02258-w

ISSN: 2041-1723