Periodic Reporting for period 2 - PROSPECTS (PIK3CA-Related Overgrowth Syndrome, Pluripotency, Expression in speCific Tissue and Secretion)

Overgrowth syndromes are rare genetic disorders defined by tissue hypertrophy that can be either localized or generalized. In most cases, the mutations are not inherited but occur during embryogenesis, leading to somatic mosaicism. The genes involved in overgrowth syndromes...