Selective replacement of cholesterol with cationic amphiphilic drugs enables the design of lipid nanoparticles with improved RNA delivery

Summary

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Authors: Bram Bogaert, Aliona Debisschop, Thomas Ehouarne, Hannelore P Van Eeckhoutte, Joyceline De Volder, An Jacobs, Eline Pottie, Riet De Rycke, Aurélie Crabbé, Pieter Mestdagh, Ine Lentacker, Guy G Brusselle, Christophe Stove, Sandra Verstraelen, Tania Maes, Ken R Bracke, Stefaan C De Smedt, Koen Raemdonck

Journal title: Nano Letters

Journal publisher: American Chemical Society

Published year: 2024

DOI identifier: 10.1021/acs.nanolett.3c03345

ISSN: 1530-6984