Periodic Reporting for period 1 - PROS-VARIANT (PIK3CA-Related Overgrowth Spectrum: molecular mechanisms and preclinical modelling of PIK3CA VARIANTs)

The PIK3CA-related overgrowth spectrum (PROS) includes a group of rare congenital disorders that result in abnormal tissue growth in various parts of the body, such as the vasculature, fat, muscle, bone, brain, and skin. Patients with PROS can have a wide range of clinical...