Periodic Reporting for period 1 - 2CE MECP2 (Visualising neuronal signalling dynamics within intact neuronal circuits: Deciphering the role of cell-specific MeCP2 dynamics in neuronal function and dysfunction)

The brain has a remarkable capacity to undergo ongoing changes, which allow us to adapt to our environment. Brain plasticity depends on changes in specific subsets of genes, and one key mechanism that enables brain adaptation is epigenetic modification. These modifications...