Indolequinone-Based Hypoxia-Activated Proteolysis Targeting Chimeras Selectively Degrade BRD4 in Hypoxic Cancer Cells

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Authors: Marta Serafini, Sophie A. Twigger, George Delfas, Maxim Mallerman, Elliot P. Bailey, Ewen D. D. Calder, Ester M. Hammond, Stuart J. Conway

Journal title: Journal of the American Chemical Society

Journal publisher: American Chemical Society (ACS)

Published year: 2025

DOI identifier: 10.1021/JACS.5C10240

ISSN: 0002-7863