Polygenic overlap with granulocyte counts identifies novel loci for clozapine metabolism and clozapine-induced agranulocytosis

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Authors: Elise Koch, Alexey A. Shadrin, Nadine Parker, Siobhan K. Lock, Robert L. Smith, Oleksandr Frei, Anders M. Dale, Srdjan Djurovic, Espen Molden, Kevin S. O´Connell, Ole A. Andreassen

Journal title: Neuropsychopharmacology

Journal number: 50

Journal publisher: Springer Science and Business Media LLC

Published year: 2025

DOI identifier: 10.1038/S41386-025-02054-X

ISSN: 0893-133X