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Immunosuppressive effects of new thiophene-based KV1.3 inhibitors

Project: pHioniC

Updated at: 28-04-2024

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Impact of Extracellular pH on Apoptotic and Non-Apoptotic TRAIL-Induced Signaling in Pancreatic Ductal Adenocarcinoma Ce...

Project: pHioniC

Updated at: 28-04-2024

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Periodic Reporting for period 1 - pHioniC (pH and Ion Transport in Pancreatic Cancer)

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Project acronym pHioniC

pHioniC website

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hERG1 Potassium Channel Expression in Colorectal Adenomas: Comparison with Other Preneoplastic Lesions of the Gastrointe...

Project: pHioniC

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Harnessing the hERG1/b1 integrin complex via a novel bispecific single-chain antibody: An effective strategy against sol...

Project: pHioniC

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Acid Adaptation Promotes TRPC1 Plasma Membrane Localization Leading to Pancreatic Ductal Adenocarcinoma Cell Proliferati...

Project: pHioniC

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Synergistic effects of agonists and two-pore-domain potassium channels on secretory responses of human pancreatic duct c...

Project: pHioniC

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KV11.1 Potassium Channel and the Na+/H+ Antiporter NHE1 Modulate Adhesion-Dependent Intracellular pH in Colorectal Cance...

Project: pHioniC

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Monitoring Immune Cell Function Through Optical Imaging: a Review Highlighting Transgenic Mouse Models

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Role of the Intracellular Sodium Homeostasis in Chemotaxis of Activated Murine Neutrophils

Project: pHioniC

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The A818–6 system as an in-vitro model for studying the role of the transportome in pancreatic cancer

Project: pHioniC

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Resistance to gemcitabine in pancreatic ductal adenocarcinoma: A physiopathologic and pharmacologic review

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Autoregulation of H+/lactate efflux prevents monocarboxylate transport (MCT) inhibitors from reducing glycolytic lactic ...

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Biophysical and Biomechanical Effect of Low Intensity US Treatments on Pancreatic Adenocarcinoma 3D Cultures

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Overcoming challenges of HERG potassium channel liability through rational design: Eag1 inhibitors for cancer treatment.

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Extracellular Matrix Collagen I Differentially Regulates the Metabolic Plasticity of Pancreatic Ductal Adenocarcinoma Pa...

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Acid-base homeostasis orchestrated by NHE1 defines pancreatic stellate cell phenotype in pancreatic cancer

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ECM composition differentially regulates intracellular and extracellular pH in normal and cancer pancreatic duct epithel...

Project: pHioniC

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The Interplay between Dysregulated Ion Transport and Mitochondrial Architecture as a Dangerous Liaison in Cancer.

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Project acronym pHioniC

Ion Channel Signature in Healthy Pancreas and Pancreatic Ductal Adenocarcinoma

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Protonation of Piezo1 Impairs Cell-Matrix Interactions of Pancreatic Stellate Cells

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Prognostic role of hERG1 Potassium Channels in Neuroendocrine Tumours of the Ileum and Pancreas

Project: pHioniC

Updated at: 28-04-2024

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Project acronym pHioniC

Cost-Effective Real-Time Metabolic Profiling of Cancer Cell Lines for Plate-Based Assays

Project: pHioniC

Updated at: 28-04-2024

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The context-dependent role of the Na+/Ca2+-exchanger (NCX) in pancreatic stellate cell migration

Project: pHioniC

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Project acronym pHioniC

What do cellular responses to acidity tell us about cancer?

Project: pHioniC

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Project acronym pHioniC

New Diarylamine KV10.1 Inhibitors and Their Anticancer Potential

Project: pHioniC

Updated at: 28-04-2024

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Acidic growth conditions promote epithelial-to-mesenchymal transitionto select more aggressive PDAC cell phenotypes in v...

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The Acidic Tumor Microenvironment as a Driver of Cancer

Project: pHioniC

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Pharmacological targeting of the mitochondrial calcium dependent potassium channel KCa3.1 triggers cell death and reduce...

Project: pHioniC

Updated at: 28-04-2024

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