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A mechanistically-anchored and human stem cell-based in vitro test battery for assessing liver steatogenic potential of ...

Project: ONTOX

Updated at: 01-12-2025

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From cellular perturbation to probabilistic risk assessments

Project: ONTOX

Updated at: 01-12-2025

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Prediction of the Neurotoxic Potential of Chemicals Based on Modelling of Molecular Initiating Events Upstream of the Ad...

Project: ONTOX

Updated at: 01-12-2025

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Ontogeny of drug-induced fatty liver disease (DIFLD): from key initiating events to disease phenotypes

Project: ONTOX

Updated at: 01-12-2025

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Challenges and opportunities for validation of AI-based new approach methods

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Updated at: 01-12-2025

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Unravelling drug-induced hepatic steatosis: Clinical sub-phenotypes, outcome prediction, and identification of high-conc...

Project: ONTOX

Updated at: 01-12-2025

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Project acronym ONTOX

Machine learning classification of steatogenic compounds using toxicogenomics profiles

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Updated at: 01-12-2025

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Biology-inspired dynamic microphysiological system approaches to revolutionize basic research, healthcare and animal wel...

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Updated at: 01-12-2025

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Unsupervised Representation Learning for Proteochemometric Modeling

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Updated at: 01-12-2025

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Project acronym ONTOX

Unlocking liver physiology: comprehensive pathway maps for mechanistic understanding

Project: ONTOX

Updated at: 01-12-2025

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Project acronym ONTOX

In vitro test battery for testing molecular initiating events in chemical-induced cholestasis

Project: ONTOX

Updated at: 01-12-2025

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Project acronym ONTOX

DockTox: Targeting molecular initiating events in organ toxicity through molecular docking

Project: ONTOX

Updated at: 01-07-2025

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From big data to smart decisions: artificial intelligence in kidney risk assessment

Project: ONTOX

Updated at: 01-07-2025

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Project acronym ONTOX

Report of the First ONTOX Hackathon: Hack to Save Lives and Avoid Animal Suffering. The Use of Artificial Intelligence i...

Project: ONTOX

Updated at: 01-07-2025

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Project acronym ONTOX

An AI supported case study applying in vitro studies using the ONTOX toolbox: Protocol for probabilistic risk assessment...

Project: ONTOX

Updated at: 01-07-2025

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Project acronym ONTOX

Novel clinical phenotypes, drug categorization, and outcome prediction in drug-induced cholestasis: Analysis of a databa...

Project: ONTOX

Updated at: 01-07-2025

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Project acronym ONTOX

Comprehensive benchmarking of computational tools for predicting toxicokinetic and physicochemical properties of chemica...

Project: ONTOX

Updated at: 01-07-2025

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Accessible methods and tools to estimate chemical exposure in humans to support risk assessment: A systematic scoping re...

Project: ONTOX

Updated at: 01-07-2025

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Project acronym ONTOX

The Development of a Non-Invasive Screening Method Based on Serum microRNAs to Quantify the Percentage of Liver Steatosi...

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Updated at: 01-07-2025

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Predicting Liver-Related In Vitro Endpoints with Machine Learning to Support Early Detection of Drug-Induced Liver Injur...

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Updated at: 01-07-2025

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Quantitative structure–activity relationships of chemical bioactivity toward proteins associated with molecular initia...

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Updated at: 01-07-2025

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SKIG report 2023-2024

Project: ONTOX

Updated at: 01-07-2025

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Mapping physiology: A systems biology approach for the development of alternative methods in toxicology

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Updated at: 01-07-2025

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A computational dynamic systems model for in silico prediction of neural tube closure defects

Project: ONTOX

Updated at: 01-07-2025

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The SCAHT Adverse Outcome Pathway (AOP)_HUB: A hands-on platform for information exchange, sharing, and developing AOPs

Project: ONTOX

Updated at: 01-07-2025

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Project acronym ONTOX

Developmental neurotoxicity (DNT): A call for implementation of new approach methodologies for regulatory purposes: Summ...

Project: ONTOX

Updated at: 01-07-2025

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Computational Strategies for Assessing Adverse Outcome Pathways: Hepatic Steatosis as a Case Study

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Updated at: 01-07-2025

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Project acronym ONTOX

Systematic evaluation of high-throughput PBK modelling strategies for the prediction of intravenous and oral pharmacokin...

Project: ONTOX

Updated at: 01-05-2025

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Adverse outcome pathway networks as the basis for the development of new approach methodologies: Liver toxicity as a cas...

Project: ONTOX

Updated at: 01-05-2025

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Periodic Reporting for period 2 - ONTOX (Ontology-driven and artificial intelligence-based repeated dose toxicity testin...

Project: ONTOX

Updated at: 01-05-2025

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