ERD

Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation

Project: TagIt

Updated at: 27-04-2024

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A Minimal, Unstrained S-Allyl Handle for Pre-Targeting Diels-Alder Bioorthogonal Labeling in Live Cells

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Updated at: 27-04-2024

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Azabicyclic vinyl sulfones for residue-specific dual protein labelling

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Updated at: 27-04-2024

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A fully human anti-IL-7Rα antibody promotes antitumor activity against T-cell acute lymphoblastic leukemia

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Updated at: 27-04-2024

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Spontaneous CO release from Ru(II)(CO)2-protein complexes in aqueous solution, cells, and mice

Project: TagIt

Updated at: 27-04-2024

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Chemo- and Regioselective Lysine Modification on Native Proteins.

Project: TagIt

Updated at: 27-04-2024

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A Water-Bridged Cysteine-Cysteine Redox Regulation Mechanism in Bacterial Protein Tyrosine Phosphatases

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Updated at: 27-04-2024

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Controlled masking and targeted release of redox-cycling ortho-quinones via a C–C bond-cleaving 1,6-elimination

Project: TagIt

Updated at: 27-04-2024

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Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation

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Updated at: 27-04-2024

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Chemo- and Regioselective Lysine Modification on Native Proteins

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Updated at: 27-04-2024

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Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents

Project: TagIt

Updated at: 27-04-2024

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A silicon-labelled amino acid suitable for late-stage fluorination and unexpected oxidative cleavage reactions in the pr...

Project: TagIt

Updated at: 27-04-2024

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Radical-Mediated Thiol-Ene Strategy: Photoactivation of Thiol-Containing Drugs in Cancer Cells.

Project: TagIt

Updated at: 27-04-2024

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Ethynylbenziodoxolone Reactivity in Cysteine Bioconjugation

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Updated at: 27-04-2024

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De novo design of potent and selective mimics of IL-2 and IL-15

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Updated at: 27-04-2024

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A Platform for Site-Specific DNA-Antibody Bioconjugation by Using Benzoylacrylic-Labelled Oligonucleotides

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Updated at: 27-04-2024

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Oxetane grafts site-selectively installed on native disulfides enhance protein stability and activity in vivo

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Updated at: 27-04-2024

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Norbornene probes for the study of cysteine oxidation

Project: TagIt

Updated at: 27-04-2024

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Bioorthogonal Strategy for Bioprocessing of Specific-Site-Functionalized Enveloped Influenza-Virus-Like Particles

Project: TagIt

Updated at: 27-04-2024

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Platinum-Triggered Bond-Cleavage of Pentynoyl Amide and N-Propargyl Handles for Drug-Activation

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Updated at: 27-04-2024

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Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells

Project: TagIt

Updated at: 27-04-2024

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Laying Waste to Mercury: Inexpensive Sorbents Made from Sulfur and Recycled Cooking Oils

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Updated at: 27-04-2024

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Natural product modulators of transient receptor potential (TRP) channels as potential anti-cancer agents

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Updated at: 27-04-2024

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Oxidative Activation of C-S Bonds with an Electropositive Nitrogen Promoter Enables Orthogonal Glycosylation of Alkyl ov...

Project: TagIt

Updated at: 27-04-2024

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Inverse electron demand Diels–Alder reactions in chemical biology

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Updated at: 27-04-2024

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A Fluorogenic Probe for Cell Surface Phosphatidylserine Using an Intramolecular Indicator Displacement Sensing Mechanism

Project: TagIt

Updated at: 27-04-2024

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Enhanced Permeability and Binding Activity of Isobutylene-Grafted Peptides

Project: TagIt

Updated at: 27-04-2024

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Site-Selective Modification of Proteins with Oxetanes

Project: TagIt

Updated at: 27-04-2024

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Trends in therapeutic drug conjugates for bacterial diseases: a patent review

Project: TagIt

Updated at: 27-04-2024

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Periodic Reporting for period 4 - TagIt (A Minimal-Tag Bioorthogonal Labelling Approach to Protein Uptake, Traffic and D...

Project: TagIt

Updated at: 27-04-2024

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